Human Polypeptide Muscle Growth Hormone Gdf-8 1mg/Vial
|FOB Unit Price:||US $49 US $40|
|Purchase Qty. (vials)||FOB Unit Price|
|Production Capacity:||100kg Every Month|
|Payment Terms:||T/T, Western Union, Money Gram, Bitcoin|
- Model NO.: Gdf-8 1Mg/Vial
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- Gdf-8 Appearance: White Lyophilized Powder
- Gdf-8 Minimum Order: 10 Vials
- Gdf-8 Transport Package: Super Discreet to Ensure 100% Pass Rate
- Trademark: Yuancheng
- Specification: Gdf-8 1Mg/Vial
- HS Code: 3001200010
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Solid
- Product Name: Gdf-8
- Gdf-8 Other Name: Myostatin
- Gdf-8 Shipping: Average 6 Days / Door-to-Door
- Gdf-8 Delivery: All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.)
- Transport Package: According to Order Quantity or Customer Requirents
- Origin: Hubei
|GDF-8 Chemical Name:||Growth Differentiation Factor 8|
|GDF-8 Other Names:||Myostatin|
|GDF-8 Appearance:||White Lyophilized Powder|
|GDF-8 Payment Terms:||Western Union, MoneyGram,TT, Bitcoin.|
|GDF-8 Country of Origin:||China|
Myostatin (GDF-8) is a member of the transforming growth factor-beta (TGF-beta) superfamily that is highly expressed in skeletal muscle, and myostatin loss-of-function leads to doubling of skeletal muscle mass. Myostatin-deficient mice have been used as a model for studying muscle-bone interactions, and here we review the skeletal phenotype associated with altered myostatin signaling. It is now known that myostatin is a key regulator of mesenchymal stem cell proliferation and differentiation, and mice lacking the myostatin gene show decreased body fat and a generalized increase in bone density and strength. The increase in bone density is observed in most anatomical regions, including the limbs, spine, and jaw, and myostatin inhibitors have been observed to significantly increase bone formation. Myostatin is also expressed in the early phases of fracture healing, and myostatin deficiency leads to increased fracture callus size and strength. Together, these data suggest that myostatin has direct effects on the proliferation and differentiation of osteoprogenitor cells, and that myostatin antagonists and inhibitors are likely to enhance both muscle mass and bone strength.
Myostatin (GDF-8) is known as a potent inhibitor of muscle growth and development, and myostatin is also expressed early in the fracture healing process. The purpose of this study was to test the hypothesis that a new myostatin inhibitor, a recombinant myostatin propeptide, can enhance the repair and regeneration of both muscle and bone in cases of deep penetrant injury.
Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.
Animals either lacking myostatin or treated with substances that block the activity of myostatin have significantly more muscle mass. Furthermore, individuals who have mutations in both copies of the myostatin gene have significantly more muscle mass and are stronger than normal. Blocking the activity of myostatin may have therapeutic application in treating muscle wasting diseases such as muscular dystrophy.
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